Polynucleotides (PNs) are biopolymeric chains of nucleotides known for their regenerative properties, particularly in stimulating fibroblast activity, improving hydration, and enhancing skin elasticity. They are widely used in dermatology and aesthetic medicine for skin rejuvenation, anti-aging treatments, and improving overall dermal structure. Their ability to bind water and support extracellular matrix production makes them highly effective in enhancing skin texture and repair.
Beyond aesthetics, polynucleotides play a key role in medical treatments, particularly in reducing inflammation and promoting tissue regeneration. They are used for osteoarthritis to support cartilage repair, in ophthalmology for corneal healing and dry eye syndrome, and in wound management to accelerate recovery. With ongoing research, their therapeutic applications continue to expand across multiple medical fields.
Results may vary depending
on the following factors:
age, medical history and lifestyle
Polynucleotide treatments use purified DNA fragments to stimulate your skin’s natural healing process. These molecules encourage collagen production, boost hydration, and support tissue regeneration, helping your skin repair and renew from the inside out.
They’re great for treating fine lines, skin laxity, under-eye hollows, acne scarring, dullness, and even rosacea. Polynucleotides improve skin texture, tone, and elasticity, making them ideal for anyone wanting healthier, firmer, and more radiant skin.
Fillers add immediate volume, while polynucleotides work on a cellular level to rejuvenate and regenerate the skin over time. Think of them as skin healers rather than volumisers - they focus on long-term skin quality rather than instant plumping.
Yes, it’s suitable for most adults, especially those experiencing early signs of ageing or skin fatigue. It's also an excellent choice for people who want a more natural approach to skin regeneration without altering facial volume.
Most patients notice an improvement in hydration and skin tone within 2 to 4 weeks. The regenerative benefits build over time, with optimal results seen around 6-12 weeks. Effects can last up to 6-9 months, depending on your skin and lifestyle.
Absolutely. Polynucleotides are highly biocompatible, meaning they're well accepted by the body. They’re derived from purified salmon DNA, processed to remove any allergenic substances. Side effects are minimal, usually limited to minor swelling or redness at the injection site.
Typically, a course of 3 treatments spaced 2-4 weeks apart is recommended for the best results. Maintenance treatments every 6 months help sustain the improvements in skin quality.
Yes! Polynucleotides pair well with other aesthetic treatments like microneedling and laser therapies. They can even enhance the recovery process and results of these procedures thanks to their healing properties.
Derma Cosmedic
6-8 Castle Street
Liverpool
L2 0NB
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